KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NUAK1
All Species:
12.12
Human Site:
T428
Identified Species:
20.51
UniProt:
O60285
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O60285
NP_055655.1
661
74305
T428
V
G
P
A
L
P
S
T
F
K
M
E
Q
D
L
Chimpanzee
Pan troglodytes
XP_001161041
661
74289
T428
V
G
P
A
L
P
S
T
F
K
M
E
Q
D
L
Rhesus Macaque
Macaca mulatta
XP_001098986
667
74748
T434
V
G
P
A
L
P
S
T
F
K
M
E
Q
D
L
Dog
Lupus familis
XP_538417
666
74288
A433
V
S
P
A
L
P
S
A
F
K
I
E
P
D
V
Cat
Felis silvestris
Mouse
Mus musculus
Q641K5
658
73643
P429
V
S
P
A
L
P
S
P
F
K
M
E
Q
D
L
Rat
Rattus norvegicus
Q66HE5
630
69934
S407
S
S
R
P
G
K
N
S
L
K
L
P
K
G
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508265
661
73136
F428
P
G
L
L
P
T
A
F
K
L
E
Q
E
L
C
Chicken
Gallus gallus
Q9IA88
798
88848
V420
L
Q
P
V
F
F
P
V
D
P
N
F
N
G
L
Frog
Xenopus laevis
NP_001088596
570
64876
N347
S
K
K
E
N
N
M
N
Q
G
V
V
T
Q
T
Zebra Danio
Brachydanio rerio
Q6NSM8
1187
130949
S750
H
G
S
A
L
Y
Q
S
P
S
D
S
P
P
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_649991
1427
153426
I1051
V
K
T
S
T
A
S
I
T
L
K
S
A
T
L
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q9TW45
1192
126331
G594
D
A
A
A
T
A
A
G
G
T
V
V
M
S
G
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P92958
512
58671
V288
A
V
S
P
P
D
T
V
E
Q
A
K
K
I
N
Baker's Yeast
Sacchar. cerevisiae
P06782
633
72027
D407
K
S
V
S
D
E
L
D
T
F
L
S
Q
S
P
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
97.9
91.7
N.A.
90.9
55.6
N.A.
84.2
26.1
48.5
23.5
N.A.
24.3
N.A.
22.4
N.A.
Protein Similarity:
100
99.8
98
94.4
N.A.
93.8
68
N.A.
88
42.8
61.4
36.2
N.A.
33.6
N.A.
35.8
N.A.
P-Site Identity:
100
100
100
66.6
N.A.
86.6
6.6
N.A.
6.6
13.3
0
20
N.A.
20
N.A.
6.6
N.A.
P-Site Similarity:
100
100
100
80
N.A.
86.6
40
N.A.
26.6
20
6.6
26.6
N.A.
26.6
N.A.
20
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
31.1
26.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
49.3
46.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
8
50
0
15
15
8
0
0
8
0
8
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% C
% Asp:
8
0
0
0
8
8
0
8
8
0
8
0
0
36
0
% D
% Glu:
0
0
0
8
0
8
0
0
8
0
8
36
8
0
0
% E
% Phe:
0
0
0
0
8
8
0
8
36
8
0
8
0
0
0
% F
% Gly:
0
36
0
0
8
0
0
8
8
8
0
0
0
15
8
% G
% His:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
8
0
0
8
0
0
8
8
% I
% Lys:
8
15
8
0
0
8
0
0
8
43
8
8
15
0
0
% K
% Leu:
8
0
8
8
43
0
8
0
8
15
15
0
0
8
43
% L
% Met:
0
0
0
0
0
0
8
0
0
0
29
0
8
0
0
% M
% Asn:
0
0
0
0
8
8
8
8
0
0
8
0
8
0
8
% N
% Pro:
8
0
43
15
15
36
8
8
8
8
0
8
15
8
15
% P
% Gln:
0
8
0
0
0
0
8
0
8
8
0
8
36
8
0
% Q
% Arg:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
15
29
15
15
0
0
43
15
0
8
0
22
0
15
0
% S
% Thr:
0
0
8
0
15
8
8
22
15
8
0
0
8
8
8
% T
% Val:
43
8
8
8
0
0
0
15
0
0
15
15
0
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _